UNITED NEWS INTERNATIONAL (UNI) — As many as 150 civilians and their families were evacuated out of Syria’s eastern Ghouta region.

At least two dozen of the civilians bussed out of Eastern Ghouta on Tuesday, March 13 were in need of urgent medical attention.

The United Nations negotiated the opening of a humanitarian corridor out of the rebel-held territory Monday.

The deal was struck after Syrian government forces splintered eastern Ghouta into three parts over the weekend.

It marked a significant advancement for the Syrian military, which is trying to seize back control of the rebel stronghold.

However, The Associated Press says supply routes to cities like Harasta are now cut off, meaning civilians have no access to medicine or aid.

It’s estimated there are around 400,000 civilians trapped in eastern Ghouta.

Fighting in eastern Ghouta has killed more than 1,100 civilians since mid-February.